Monotherapy for partial epilepsy: focus on levetiracetam
نویسندگان
چکیده
منابع مشابه
Levetiracetam monotherapy for newly diagnosed epilepsy patients
We retrospectively reviewed the charts of all of our patients with a history of partial seizures, with and without secondarily generalisation, who received levetiracetam (LEV; Keppra) for treatment of their seizures during the years 2000-2002. Forty-five patients were identified, 13 of whom began LEV as first line therapy. Eleven patients continued on LEV for at least 6 months; six of whom beca...
متن کاملLevetiracetam monotherapy for elderly patients with epilepsy
We retrospectively identified 14 elderly patients with a history of partial seizures who received levetiracetam (LEV) monotherapy. Patients began LEV either as first line therapy (n=5) or were converted to LEV monotherapy (n=9) after failing prior antiepileptic medications (AEDs). Thirteen patients continued on LEV monotherapy for at least 6 months. One patient was lost to follow-up. Eight pati...
متن کاملLevetiracetam monotherapy for primary generalised epilepsy
PURPOSE To evaluate the efficacy of levetiracetam in cases of refractory primary generalised epilepsy. METHODS Three patients with refractory primary generalised epilepsy were treated with levetiracetam monotherapy; one with absence seizures, myoclonic jerks and generalised tonic-clonic (GTC) seizures one with myoclonic jerks and GTC seizures, and one with only GTC seizures. All three patient...
متن کاملTreatment of Epilepsy: Focus on Levetiracetam
− A good balance between safety and tolerability is necessary for an antiepileptic drug (AED) to be successful in the management of patients with epilepsy. Levetiracetam is one of the new generation of AEDs licensed as an add-on therapy for the treatment of patients with partial-onset seizures. Levetiracetam’s mechanisms of action are not fully understood. Controlled clinical trials, open-label...
متن کاملTreatment of Epilepsy: Focus on Levetiracetam
− The pharmacokinetic properties of a drug are the primary determinant of the extent and duration of drug action, and influence susceptibility to clinically important drug interactions. Most of the older-generation antiepileptic drugs (AEDs) are far from ideal in terms of pharmacokinetics and interaction potential. For example, phenytoin, carbamazepine, and valproic acid exhibit non-linear kine...
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ژورنال
عنوان ژورنال: Neuropsychiatric Disease and Treatment
سال: 2008
ISSN: 1176-6328
DOI: 10.2147/ndt.s1655